EnBIO: CoBlast™ - Drug Delivery Surface

By: Enbio  05/12/2011
Keywords: Drug delivery, Drug Eluting Surface, Metallic Implant Surfaces,

EnBIO's third offering is a drug eluting surface for metallic medical implants. Work on this is ongoing. However, the initial draft specification has three main components.

  • Possibility of eluting a broad range of drugs. Initial focus is on antibiotics
  • Applicable to the full range of metallic implant surfaces (Ti, NiTi, CoCr and various Stainless Steels)
  • Customizable elution profile,
    • few hours (e.g. as a burst of antibiotics for infection control in the immediate time after the surgery)
    • few days (e.g. 10 days for general infection control)
    • few months (e.g. 2 to 3 months elution of sirolimus for drug eluting stents)
  • The drug cannot elute at concentrations less than the Minimum Effective Concentration (MEC) in the case of antibiotics

Keywords: Drug delivery, Drug Eluting Surface, Metallic Implant Surfaces, Metallic Medical Implants,

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