Process Development

By: Celtic Catalysts  05/12/2011

Our team has many combined years of experience in turning medchem routes into successful plant-scale synthesis, and in optimising existing plant and pilot plant processes. We use high throughput screening equipment to identify optimum conditions and have excellent facilities for the analysis of product purity. These processes can then be scaled up by our production chemists and a fully optimised “tech package” is then transferred back to the customer.


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Other products and services from Celtic Catalysts



We recognise the importance of high purity amino acids for peptide drug manufacturers and consequently we produce our amino acids and derivatives to an ultra-high purity specification. Celtic Catalysts has a portfolio of internally-developed chiral technologies which we use to produce amino acids in laboratory to production-scale quantities.


Amino Acids

Our highly effective asymmetric hydrogenation catalysts enable us to make this in exceptionally high purityand enantiomeric excess. If you require a custom, bespoke unnatural amino acid, we have a range of experience covering various amino acids groups. Celtic Catalysts specializes in the manufacture of unnatural, unusual, difficult-to-make amino acids.



The full reports supplied at the close of each project are always prepared by the lead chemist and include complete, publication/patent-quality characterisation of novel compounds where possible. We have first class synthesis and analytical facilities at our disposal which enable us to capitalise upon our expertise and provide a broad range of the highest quality services to our clients.


Catalyst Screening

In addition to our own in-house ligands and catalysts, we also screen other companies' proprietary and non-proprietary catalysts using parallel multi-well hydrogenation reactors including the Biotage Endeavor. If you require a more efficient catalyst or believe a catalytic hydrogenation is a superior option to your current chemistry we can help you find the optimum route.


Custom Synthesis

Our custom synthesis services can be secured to produce milligram to multi-kilogram quantities of compounds from either known processes or from new processes developed by our team. We relish taking on difficult synthetic challenges and encourage you to seek a quotation for all of your custom synthesis needs. We achieve this with high levels of communication and customer service. Raw Material/building block synthesis - grams and kilos.