Custom Synthesis

By: Celtic Catalysts  05/12/2011

Our custom synthesis services can be secured to produce milligram to multi-kilogram quantities of compounds from either known processes or from new processes developed by our team. We relish taking on difficult synthetic challenges and encourage you to seek a quotation for all of your custom synthesis needs. Previous projects have covered the following activities:

  • Metabolite and impurity synthesis - gram scale
  • Raw Material/building block synthesis - grams and kilos
  • Novel compound design and synthesis
  • Building block scale-up and supply (grams and kilos)
  • Synthesis of analogs and libraries
  • Chiral Synthon synthesis and supply

Our highly experienced team of chemists are capable of delivering on a wide range of projects from post med-chem library stage right through to clinical trials. Our aim is to provide you with a custom synthesis service that will feel like part of your own organisation. We achieve this with high levels of communication and customer service. Contact us now for a quotation.


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Other products and services from Celtic Catalysts

05/12/2011

Products

We recognise the importance of high purity amino acids for peptide drug manufacturers and consequently we produce our amino acids and derivatives to an ultra-high purity specification. Celtic Catalysts has a portfolio of internally-developed chiral technologies which we use to produce amino acids in laboratory to production-scale quantities.


05/12/2011

Amino Acids

Our highly effective asymmetric hydrogenation catalysts enable us to make this in exceptionally high purityand enantiomeric excess. If you require a custom, bespoke unnatural amino acid, we have a range of experience covering various amino acids groups. Celtic Catalysts specializes in the manufacture of unnatural, unusual, difficult-to-make amino acids.


05/12/2011

Services

The full reports supplied at the close of each project are always prepared by the lead chemist and include complete, publication/patent-quality characterisation of novel compounds where possible. We have first class synthesis and analytical facilities at our disposal which enable us to capitalise upon our expertise and provide a broad range of the highest quality services to our clients.


05/12/2011

Catalyst Screening

In addition to our own in-house ligands and catalysts, we also screen other companies' proprietary and non-proprietary catalysts using parallel multi-well hydrogenation reactors including the Biotage Endeavor. If you require a more efficient catalyst or believe a catalytic hydrogenation is a superior option to your current chemistry we can help you find the optimum route.


05/12/2011

Process Development

Our team has many combined years of experience in turning medchem routes into successful plant-scale synthesis, and in optimising existing plant and pilot plant processes. These processes can then be scaled up by our production chemists and a fully optimised “tech package” is then transferred back to the customer.